Theranostics
At KIT, we focus on highly interdisciplinary activities in the field of diagnostics and therapy ("theranostics”), We aim to revolutionize molecular diagnostic capabilities by developing new concepts, systems, and technologies that can provide the base for an affordable and robust application in clinics, point-of-care units, and homes, both in developed and developing countries. We develop strategies to overcome the outdated “organ-focused” definition of diseases by in-depth investigation of metabolomic pathways and pathogenic mechanisms to arrive at a molecular mechanism-centered disease description.
Projects
Theranostics Initiative (Bräse/ IBCS-FMS, Biedermann/INT, Feldmann/AOC, Schepers/IFG, Orian-Rousseau/ IBCS-FMS, Levkin/ IBCS-FMS, Luy/ IBG-4, Muhle-Goll/IBG-4, Korvink/ IMT)
Intelligent sensors and wearables to track and analyse users behaviour in the mobility system (Knoch, MoBiSys/ Gauterin, Institute 2)
Microfluidic point-of-care biosensors (Dominguez, Niemeyer, Rabe/ IBG1)
Developing new molecular entities, smart materials, miniaturized high content screening methods as well as design of novel biomedical tools for the treatment of diseases (Bräse/ IOC, IBCS-FMS)
Multidiagnosis (Breitling, Mager, Weber/IMT Terzides Entechnon)
Synthetic receptors (SRs) and novel assays for the continous and rapid detection of biomarkers in biofluids (Biedermann, DeCola/IFG)
Quantifying lung perfusion parameters (Nestler/ INT, Koeppe)
Measuring the drug concentrations in blood or plasma, or in other biological fluids that can be linked to blood drug concentrations (Ates/ ITS)
Simultaneous release and monitoring of drug cocktail for effective reduction of resistances and metastases of tumors (Feldmann/ AOC, Schepers/ IFG, Bräse/ IOC)
Advanced inorganic nanocrystals for short wavelength infrared imaging and alpha radiotherapy (Hudry/ IMT, Richards/ IMT, Orian-Rousseau/ IBCS-FMS)
Parallelized Diagnostics (Orian-Roussau/ IBCS-FMS, Nesterov-Müller, IMT)
Organ-specific drug transport (Schepers/IFG, Feldmann/ AOC, Bräse/ IOC)
Identification of markers or marker patterns for civilization diseases Organ-specific drug transport (Luy, Muhle-Goll/ IBG-4)
